Essential tremor is a common movement disorder that causes rhythmic shaking, usually in the hands, head, or voice. People with essential tremor often notice shaking when using their muscles, like drinking from a cup or writing, and stress or caffeine can make it worse. It tends to be long-lasting and may slowly worsen over years, with many first noticing early symptoms of essential tremor in adolescence or adulthood. Not everyone will have the same experience, and it does not shorten life for most people. Treatments include lifestyle adjustments, medicines like propranolol or primidone, and for more severe essential tremor, options such as focused ultrasound or deep brain stimulation.

Overview

Essential tremor

Symptoms

Essential tremor causes rhythmic shaking, usually in the hands, that gets worse with movement like writing, eating, or holding a cup. It can also affect the head or voice. Stress, fatigue, or caffeine may make symptoms more noticeable.

Outlook and prognosis

Many people with Essential tremor live full, active lives, though hand shaking can slowly increase over years. Symptoms often improve with tailored treatment and lifestyle adjustments. For most, life expectancy is typical; planning supports independence at home and work.

Causes and risk factors

Essential tremor often has no clear cause; many cases run in families (usually autosomal dominant). Risk rises with age. Triggers and risk modifiers include stress, caffeine, certain medicines, nicotine, thyroid disease, and possible environmental toxins; alcohol may briefly lessen tremor.

Genetic influences

Genetics play a major role in Essential tremor. About half of people have a family history, often passed in an autosomal dominant pattern, meaning a parent with ET can pass risk to children. Specific gene variations are being studied but aren’t routine tests yet.

Diagnosis

Diagnosis of essential tremor relies on history and a focused neurologic exam, watching tremor during actions like writing or holding a cup. Doctors rule out other causes with medication review, targeted labs, and, if features are atypical, brain imaging.

Treatment and drugs

Treatment for essential tremor focuses on easing shaking so daily tasks feel steadier. Options may include lifestyle steps (sleep, less caffeine), targeted medicines like propranolol or primidone, wrist weights or occupational therapy, and, for difficult cases, botulinum toxin, focused ultrasound, or deep brain stimulation. Plans are individualized and reviewed over time to match goals and side effects.

Symptoms

Essential tremor can make everyday tasks feel shaky, like holding a cup or signing your name. Symptoms vary from person to person and can change over time. People often notice early symptoms of Essential tremor during movement—pouring coffee, using utensils, or typing—rather than when the hands are fully at rest. It usually starts in the hands and forearms and may later involve the head or voice.

Action tremor

Shaking happens during movement or when holding a position, not when the muscles are completely at rest. In Essential tremor, this is most noticeable when reaching, writing, or eating. The tremor can ease briefly when the hands are supported.

Hands most affected

The hands and forearms are usually where shaking shows up first. Essential tremor often affects both sides, though one side may shake more. Fine tasks like buttoning or threading a needle can become harder.

Head nodding

The head may move in a yes-yes or no-no pattern. This can be subtle at first and more visible in photos or video calls. Neck muscles are not weak; the movement comes from rhythmic signals to the muscles.

Voice shakiness

A wavering, shaky voice can make speech sound uneven in volume or pitch. Talking for long periods or speaking loudly may make it more noticeable. Some find it harder to project their voice in noisy spaces.

How people usually first notice Essential tremor?

Many people first notice essential tremor when a hand starts to shake during everyday tasks—holding a cup, using a key, or writing—especially when they’re stressed, tired, or have caffeine. The shaking typically shows up when the muscles are active (action or postural tremor), not when fully at rest, and it often eases a bit with small amounts of alcohol, which some report as an early clue. Family members may point out a long-standing “shaky hands” pattern, since essential tremor often runs in families, and over time the tremor can involve the head or voice, prompting people to seek care.

Dr. Wallerstorfer Dr. Wallerstorfer

Types of Essential tremor

Essential tremor can look different from person to person, and the pattern often shapes daily life—pouring coffee, writing a note, or holding a phone steady. Broadly, symptoms are grouped into types based on when and where the tremor shows up. Not everyone will experience every type. Understanding the common types of Essential tremor can help you describe what you notice and talk about the types of Essential tremor with your clinician.

Action tremor

Shaking appears when using the muscles, like reaching for a glass or buttoning a shirt. It tends to ease when the limb is fully at rest. For many, certain types stand out more than others.

Postural tremor

Tremor shows up when holding a position against gravity, such as extending your arms to take a photo. It may settle once the arms are supported or rested.

Kinetic tremor

Shaking increases while the limb is moving through space, like bringing a spoon to your mouth. Movements that require precision can make it more noticeable.

Intention-predominant

Tremor grows larger as your hand approaches a target, such as touching your nose or signing your name. It can make fine tasks slow or tiring.

Head and voice

Some people develop a yes–no or side-to-side head tremor, a shaky voice, or both. Speech may sound quivery, and holding the head steady for photos can be hard.

Leg and trunk

Less common, tremor can affect the legs or body core, making standing still or balance tasks feel unsteady. Walking may be normal, but standing in line can be challenging.

Unilateral onset

Tremor starts on one side, often the dominant hand, and may later involve both sides. Early symptoms of Essential tremor can be subtle, like a slight shake pouring water.

Alcohol-responsive

A small amount of alcohol temporarily eases tremor for some, though this is not a treatment plan. The effect wears off and should not be used to manage symptoms.

Task-specific

Tremor mainly appears during particular tasks, such as writing or using utensils. Outside those tasks, shaking may be minimal or absent.

What genetics can tell you about symptoms

Certain genetic changes, especially in LINGO1 and STK32B, are linked to earlier onset and a stronger, rhythmic hand or head tremor that worsens with action. In some families, these variants also increase voice tremor and balance difficulties without affecting thinking.

Dr. Wallerstorfer Dr. Wallerstorfer

Causes and risk factors

Essential tremor likely involves changes in how brain circuits control movement, but the exact cause is still unknown.
Having risk factors doesn’t mean you’ll definitely develop the condition.
It often runs in families, and a parent with Essential tremor can pass on a higher chance to their children.
Risk factors for Essential tremor include getting older, with many cases starting in midlife or later.
Triggers that can worsen tremor include caffeine, stress, and lack of sleep, and some medicines or stimulants can also make it worse.

Environmental and biological risk factors

Essential tremor often shows up during everyday tasks—holding a cup, using cutlery, or writing a note—and can feel more noticeable in busy or stressful moments. That said, biology and environment work hand in hand. Below are environmental and biological factors that can raise risk for essential tremor or make it more visible day to day. Sometimes early symptoms of essential tremor surface during illness or high-pressure situations, then settle once the trigger passes.

Advancing age

The chance of developing essential tremor increases as the nervous system changes over time. Age-related shifts in brain wiring can make movement-control circuits less steady.

Cerebellar circuit changes

Changes in the cerebellum and its connections can drive rhythmic signals that produce tremor. This biological vulnerability can raise the likelihood and severity of shaking.

GABA signaling differences

Lower activity of the brain’s main calming messenger (GABA) can let overactive tremor signals break through. This imbalance may make hand or head shaking more pronounced.

Stress and anxiety

Surges of adrenaline tighten muscles and can amplify tremor. Many living with essential tremor notice shaking becomes more obvious during public speaking, deadlines, or medical appointments.

Genetic risk factors

For many living with Essential tremor, genetics plays a major role. It often runs in families, sometimes in a pattern where a parent with tremor has about a 50% chance of passing on the predisposition, and early symptoms of Essential tremor may show up at a younger age in some families. Risk is not destiny—it varies widely between individuals. No single ET gene explains most cases; instead, several common and rare genetic changes can nudge risk upward to different degrees.

Gene illustration
  • Runs in families: In many families, tremor follows an autosomal dominant pattern, so each child of an affected parent has about a 50% chance to inherit the predisposition. Expression varies, so who develops tremor and how severe it becomes can differ widely within the same family.

  • Multiple small effects: Most people’s risk comes from many common genetic changes, each adding a small amount. Together they can raise susceptibility, but no single change is usually decisive.

  • Variable penetrance: Some people inherit the same risk change yet never develop tremor, while others do later in life. This age-related penetrance can make it look like the condition skips generations.

  • Common risk variants: Variants near genes involved in nerve insulation and brain signaling (for example, LINGO1 and STK32B) show small but reproducible links to Essential tremor in large studies. They increase odds modestly and do not cause tremor on their own.

  • Rare familial variants: Uncommon changes in certain genes (such as FUS, HTRA2, or TENM4) have been found in a few multi-generation families with tremor. These are rare and still being studied, and they do not explain most cases.

  • Population differences: Some risk variants are more or less common in specific ancestries, which can shift how often familial tremor is seen in different groups. This helps clarify why genetic study findings may vary across regions.

  • Sporadic cases: Many people with Essential tremor have no clear family history. This likely reflects complex inheritance, new changes, or risk spread across many genes below the threshold that relatives would notice.

  • Testing today: There is currently no single clinical genetic test that confirms most Essential tremor. Genetic counseling can help interpret family patterns and discuss whether research-based or targeted testing makes sense.

Dr. Wallerstorfer Dr. Wallerstorfer

Lifestyle risk factors

Essential tremor is not caused by lifestyle habits, but daily choices can influence how noticeable the tremor is and how much it affects function. Understanding how lifestyle affects Essential tremor can help you anticipate and reduce flares. The elements below highlight practical lifestyle risk factors for Essential tremor and ways to modify them for symptom control.

Caffeine and stimulants

Caffeine, energy drinks, and other stimulants can amplify tremor amplitude by increasing adrenergic drive. Reducing total intake or avoiding it before fine-motor tasks may lessen visible shaking.

Alcohol use

Small amounts of alcohol can briefly reduce tremor in some people, but regular or heavy use often leads to rebound worsening and dependence risk. Avoid relying on alcohol for tremor control and discuss safer options with your clinician.

Nicotine

Nicotine activates the sympathetic nervous system and can make hand tremor more pronounced. Cutting back or quitting may reduce tremor intensity during waking hours.

Sleep deprivation

Short or fragmented sleep heightens tremor by increasing physiologic arousal and fatigue. A consistent sleep schedule may smooth out day-to-day variability in tremor severity.

Risk prevention

You can’t fully prevent essential tremor, but many people can lower triggers and protect steadiness with daily habits and care. If you notice early symptoms of essential tremor, getting help early may make day-to-day tasks easier. Talk to your doctor about which preventive steps are right for you. Prevention centers on avoiding triggers, building steadiness, and preventing injuries.

Limit stimulants

Cut back on caffeine from coffee, tea, energy drinks, and some sodas. Decongestants and other stimulants can also worsen tremor—ask about safer options.

Manage stress

Stress and anxiety can make tremor more noticeable. Try brief daily practices like breathing exercises, gentle yoga, or short walks to ease body tension.

Steady sleep

Aim for a regular sleep schedule and 7–9 hours nightly. Good sleep often calms the nervous system and can reduce daytime shakiness.

Alcohol caution

A small amount may briefly steady a tremor, but effects fade and rebound tremor can follow. Avoid heavy drinking and binge use, and ask about safer options.

Transmission

Essential tremor is not contagious—you can’t catch it from someone, and you can’t give it to others. In many families, essential tremor follows a pattern where a change in one copy of a gene is enough to cause it, so if a parent has essential tremor, each child has about a 50% chance of developing it.

This is the most common way essential tremor is passed on, and explains how Essential tremor is inherited for many people, but some develop essential tremor with no family history because of a new genetic change. Even within the same family, the tremor can start at different ages and range from very mild to more noticeable.

Gene illustration

When to test your genes

Consider genetic testing if you developed essential tremor before age 40, have multiple close relatives with tremor across generations, or your symptoms are severe or unusual. Testing can clarify inherited risk, guide medication choices, and inform screening for related conditions. Talk with a neurologist or genetic counselor to decide the right timing.

Dr. Wallerstorfer Dr. Wallerstorfer

Diagnosis

Shaking that shows up when you hold a cup, write a note, or reach for a key often prompts the first medical visit. Doctors usually begin by listening to your story and watching how the tremor behaves during everyday movements. There isn’t a single test for essential tremor; the pattern over time and ruling out other causes guide how essential tremor is diagnosed. The diagnosis of essential tremor is based on what you report, what the exam shows, and a few targeted tests to exclude look-alike conditions.

Medical history

Your provider asks when the tremor started, what brings it on, and how it affects daily tasks. They review medicines, caffeine and alcohol use, and family history, since essential tremor can run in families.

Neurologic exam

The exam checks whether the tremor appears with action or posture rather than at rest. Your provider looks for features that suggest other causes, such as stiffness or slowness that would point toward Parkinson’s disease.

Task-based checks

You may be asked to hold your arms out, touch your finger to your nose, pour water, or draw a spiral. These simple tasks show how strong and steady the tremor is and how much it interferes with function.

Lab tests

Blood work can check thyroid levels and look for metabolic issues that can cause or worsen shaking. ... and other lab tests may help rule out common conditions.

Stages of Essential tremor

Essential tremor does not have defined progression stages. Symptoms often change slowly over years and can vary day to day, so clinicians usually describe how much the tremor affects tasks like writing, eating, or holding a cup rather than placing it into fixed stages. Doctors usually start with a conversation about your tremor pattern, early symptoms of essential tremor, medicines, caffeine or alcohol use, and a hands-on exam to watch the tremor at rest and with action. To monitor, they may repeat simple movement tests over time and, if needed, order blood work or imaging to rule out other causes, since there’s no single lab test for essential tremor.

Outlook and prognosis

Many people ask, “What does this mean for my future?”, and for Essential tremor the outlook is often measured in function—how well you can write, eat, type, pour a drink, or keep doing work and hobbies. The condition tends to progress slowly over years, with tremor amplitude usually increasing and sometimes spreading from the hands to the head or voice. Everyone’s journey looks a little different. Some people need to adapt utensils or use weighted tools; others benefit from medication tweaks or therapy and keep most daily tasks manageable.

Looking at the long-term picture can be helpful. Doctors call this the prognosis—a medical word for likely outcomes. Essential tremor is not considered dangerous by itself and does not reduce life expectancy in most people. That said, severe tremor can raise fall risk, contribute to social withdrawal, and make eating or taking medicines harder, so treating early symptoms of Essential tremor and staying active can protect overall health. A small subset may notice tremor getting more disabling with age; advanced options like focused ultrasound or deep brain stimulation can restore function for many when medicines no longer do enough.

With ongoing care, many people maintain independence for decades. The outlook is not the same for everyone, but combining treatment, practical tools, and support usually keeps quality of life high. Talk with your doctor about what your personal outlook might look like. If you’re noticing changes—more spills, a shakier signature, voice tremor—ask about adjustments now rather than waiting; small changes can have a big impact on day-to-day life.

Long-term effects

Essential tremor tends to evolve slowly over years, and the impact can look different from one person to another. Long-term effects vary widely, and changes often come in small steps rather than sudden shifts. Most people have a usual life span, though daily tasks may become more effortful as tremor grows. Early symptoms of essential tremor are often small hand shakes during use that gradually become more noticeable.

Gradual progression

Tremor strength often increases slowly over decades. It may interfere more with tasks like eating or writing as years pass. The pace can be uneven, with periods of little change.

Spread to new areas

Tremor may start in one hand and later involve both hands, the head, or the voice. Essential tremor can cause a gentle “yes-yes” or “no-no” head shake or a shaky voice. Not everyone experiences spread beyond the hands.

Hand function limits

Writing, using utensils, grooming, or fastening buttons can become harder. People with essential tremor often need extra time or effort for fine tasks. Fatigue after detailed work is common.

Voice and speech

A quivering or shaky voice can develop over time. Speaking for long periods may feel tiring or strained. Phone calls and public speaking may feel more challenging.

How is it to live with Essential tremor?

Living with essential tremor often means planning around shakiness in the hands or head that’s most noticeable when you’re doing things—writing, drinking from a cup, buttoning a shirt, using utensils, or holding a phone. Symptoms can ebb and flow with stress, caffeine, fatigue, or certain medicines, so many people learn small workarounds like weighted utensils, two‑handed grips, voice‑to‑text, or timing tasks when tremor is quieter. It usually doesn’t change life expectancy, but it can affect confidence and social comfort; friends, family, and coworkers may need simple awareness and patience, like pouring drinks, opening packages, or allowing extra time for fine‑motor tasks. For many, the right mix of treatment, practical tools, and support restores control over day‑to‑day life, even if the tremor remains.

Treatment and drugs

Essential tremor treatment focuses on easing shaking so daily tasks feel easier, like drinking from a cup or writing a note. Medicines that ease symptoms are called symptomatic therapies, and common options include propranolol or primidone; if these aren’t enough or cause side effects, other drugs such as topiramate, gabapentin, or benzodiazepines may be tried with careful monitoring. For tremor that disrupts work or self‑care despite medication, device-based treatments like focused ultrasound or deep brain stimulation can help by calming the brain signals that drive the tremor. Alongside medical treatment, lifestyle choices play a role: reducing caffeine and alcohol, using weighted utensils, occupational therapy, and stress management can all make tremor less noticeable. Not every treatment works the same way for every person, so your doctor can help weigh the pros and cons of each option and adjust over time.

Non-drug treatment

Essential tremor care often starts with practical changes that make daily tasks steadier and less tiring. Alongside medicines, non-drug therapies can protect function, reduce embarrassment, and improve confidence at home and work. These approaches are tailored to your goals—cooking, typing, eating, or signing forms—and can be adjusted as tremor changes over time. These steps can help even when early symptoms of essential tremor begin to interfere with daily tasks.

Occupational therapy

A therapist helps you adapt tasks like eating, dressing, typing, and phone use. They suggest tools and set‑ups that make essential tremor less disruptive at home and work.

Physical therapy

Targeted exercises improve posture, strength, and balance to steady movements. This can lower fall risk and make walking, carrying, and reaching feel more controlled.

Stress reduction

Supportive therapies can calm the body’s stress response that often worsens tremor. Options include breathing practice, mindfulness, and biofeedback.

Sleep routine

Regular, sufficient sleep can reduce tremor flare‑ups during the day. Treating snoring or sleep apnea and keeping a steady bedtime often helps essential tremor.

Your genes may have an impact on how drugs work for you

Genes can change how your body processes tremor medicines—some people break them down quickly and need higher doses, while others clear them slowly and feel more side effects. Pharmacogenetic testing can sometimes guide safer choices, but careful dose trialing still matters.

Dr. Wallerstorfer Dr. Wallerstorfer

Pharmacological treatments

Many living with essential tremor use medication to steady their hands enough to write, eat, or hold a cup, especially when early symptoms of essential tremor begin to disrupt everyday tasks. First-line options usually include propranolol and primidone, with others added or swapped based on response and side effects. Injections such as botulinum toxin can help when tremor affects the head or voice, or when tablets aren’t enough. Not everyone responds to the same medication in the same way.

Propranolol

A beta-blocker that can lessen hand and head tremor in many people. It may be taken daily or before events that trigger symptoms. Common side effects include tiredness, lightheadedness, or low blood pressure, and it may not suit those with asthma.

Primidone

An anti-seizure medicine that often helps when beta-blockers aren’t enough. Dosing may be increased or lowered gradually to balance tremor control with side effects like sleepiness or nausea. Starting low and slowing increases can improve tolerability.

Topiramate

Can reduce tremor for some when first-line drugs fall short. Possible side effects include tingling in fingers, weight loss, and word-finding difficulty. It’s usually added slowly and adjusted based on response.

Gabapentin

May ease tremor in people who cannot take other options or need an add-on. It is generally well tolerated but can cause sleepiness or dizziness. Benefits may be modest and vary by person.

Genetic influences

Many families notice that essential tremor tends to show up across generations. In many cases, the tendency is inherited in a way that, if a parent has essential tremor, each child has about a 50% chance of inheriting the susceptibility. Having a genetic risk is not the same as having the disease itself. Not everyone who inherits this tendency will develop tremor, and for those who do, the age it starts and how much it interferes with daily tasks can vary widely—even within the same family.

Researchers have found several gene changes linked to higher risk, but there isn’t one single “essential tremor gene”; it’s likely influenced by a mix of genes and life factors. In families with essential tremor, early symptoms of essential tremor may appear in the teen years or not until later adulthood, and they may stay mild for a long time. If several relatives are affected, let your clinician know; genetic counseling can help explain inheritance and discuss family planning even when a specific genetic test isn’t available.

Is Essential tremor genetic?

Genetics play a major role in Essential tremor. About half of people have a family history, often passed in an autosomal dominant pattern, meaning a parent with ET can pass risk to children. Specific gene variations are being studied but aren’t routine tests yet.


Pharmacogenetics—how genetics influence drug effects

Two people with essential tremor can take the same dose of propranolol or primidone and have very different results—one might get steadier hands, while another mainly feels sleepy or light‑headed. Genes can influence how quickly you process certain tremor medicines, which can change how strong the effect is and how likely side effects are. Some people naturally break down beta‑blockers and anti‑seizure medicines faster, so the drug may not last long enough to help; others process them more slowly and may need lower doses to avoid dizziness, fatigue, or excessive sedation. Family patterns in essential tremor don’t currently tell doctors which drug will work best, and pharmacogenetic testing isn’t routine for this condition, but it may be considered if you’ve had unusual reactions or little benefit from several options. Other factors still matter—age, other medicines, caffeine or nicotine use, and liver health can all shift how these drugs behave. If medication response in essential tremor has been hard to predict, a conversation about potential drug–gene interactions can help your care team tailor the choice and dose to you.

There are 0 Drugs to treat Essential tremor
Currently no available information

Interactions with other conditions

Shaking often feels worse when another health issue is in the mix. Essential tremor can be mistaken for, and may coexist with, Parkinson’s disease; some people later develop features of both, which can change treatment choices. Anxiety, depression, and sleep problems are common alongside Essential tremor and can amplify the tremor, especially during stress or fatigue. Doctors call it a “comorbidity” when two conditions occur together. Thyroid overactivity, fever, or stimulants such as caffeine and certain asthma inhalers can make tremor surge; alcohol may briefly steady the hands but can backfire with rebound shakiness and dependence risk. Beta-blockers used for Essential tremor may worsen asthma or hide low-blood-sugar warning signs in diabetes, so plans often need adjusting when these conditions are present. Some people with Essential tremor also live with migraine, and mild thinking or memory changes have been reported, though this varies widely. Coordinated care helps balance tremor control with safety across your other health needs.

How genes can cause diseases

Humans have more than 20,000 genes, each carrying out one or a few specific functions in the body. One gene instructs the body to digest lactose from milk, another tells the body how to build strong bones and another prevents the body's cells from beginning to multiply uncontrollably and developing into cancer. As all of these genes combined are the building instructions for our body, a defect in one of these genes can have severe health consequences.

Through decades of genetic research, we know the genetic code of any healthy/functional human gene. We have also identified that in certain positions on a gene, some individuals may have a different genetic letter from the one you have. We call these hotspots "Genetic Variations" or "Variants" in short. In many cases, studies have been able to show that having the genetic letter "G" in the position makes you healthy, but having the letter "A" in the same position disrupts the gene function and causes a disease. Genopedia allows you to view these variants in genes and summarizes all that we know from scientific research, which genetic letters (Genotype) have good or bad consequences on your health or on your traits.

History

Throughout history, people have described hands that shake more when reaching for a cup or writing a note, while resting tremor was less of a problem. Community stories often described the condition as “nerves” or “shakes,” especially in older relatives who learned to steady a spoon with two hands or avoid carrying a full glass. These everyday workarounds show up again and again in family memories across countries and languages.

First described in the medical literature as a rhythmic, action-related tremor, essential tremor was long defined by what doctors could observe: a visible shake during movement, often in both hands, sometimes involving the head or voice. Early reports called it “benign tremor,” though the term has gradually fallen out of use because the shaking can interfere with daily life, work, and social activities. Over time, descriptions became more precise, separating essential tremor from other causes of shaking like Parkinson’s disease, thyroid problems, medication effects, or alcohol withdrawal.

From early theories to modern research, the story of essential tremor tracks with advances in brain science. As medical science evolved, careful examination and long-term follow-up showed that many people with essential tremor have family members with similar symptoms, and that tremor often grows more noticeable with age. In recent decades, awareness has grown that essential tremor is common, not rare, and that it varies: for some, it stays mild; for others, it can become more pronounced or spread to the head or voice.

Advances in genetics and brain imaging added new layers. Family studies highlighted inherited patterns in many, while also showing that essential tremor can appear in people with no known family history. Imaging and pathology work pointed to changes in brain circuits that fine-tune movement, especially in areas that act like a stabilizer for precise tasks. These historical steps helped refine today’s approach: diagnose essential tremor based on pattern and exam, rule out other conditions, and tailor treatment to how much the tremor affects everyday life.

Looking back helps explain why definitions shifted. Not every early description was complete, yet together they built the foundation of today’s knowledge. That history shapes current care—recognizing early symptoms of essential tremor, understanding its variability, and offering support and treatment options that match each person’s goals.

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